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Gastroenterology

  1. A Review of Helicobacter Pylori2015/04/02
    A review article in the April 2015 issue of Gastroenterology looks at the effects of Helicobacter pylori infection and challenges to and benefits of its eradication.
  2. Mucosal Impedance Discriminates GERD from Non-GERD Conditions2015/04/02
    A study in the February issue of Gastroenterology looked at mucosal impedance (MI) patterns in patients with GERD and common nonreflux conditions, to assess MI patterns before and after treatment with proton pump inhibitors and to compare performance.
  3. A Review of Gut–Liver Axis in Alcoholic Liver Disease2015/02/13
    A review article in the January issue of Gastroenterology summarizes recent findings and highlights emerging trends in the gut–liver axis relevant to alcoholic liver disease. Dr. Kuemmerle interviews author Dr. Gyongyi Szabo
  4. Clinical Management of Eosinophilic Esophagitis2014/12/31
    A review article in the December issue of Gastroenterology looks at current options and new advances in management of eosinophilic esophagitis. Dr. Kuemmerle speaks with the co-author of this review, Dr. Evan Dellon.
  5. Comparing Fecal Immunochemical Tests and Colonoscopy in Familial Colorectal Cancer Screening2014/11/26
    A study in the November issue of Gastroenterology shows results of a controlled randomized trial to compare the efficacy of repeated fecal immunochemical tests (FITs) and colonoscopy in detecting advanced neoplasia in family members of patients w/ CRC.
  6. Risk of Upper Gastrointestinal Bleeding from Combinations of Drugs2014/10/15
    A study in the October issue of Gastroenterology estimates the risk of upper gastrointestinal bleeding during concomitant use of nonselective (ns)NSAIDs, cyclooxygenase -2 selective inhibitors (COX-2 inhibitors), and low-dose aspirin with other drugs.
  7. Vedolizumab for Crohn's Patients After TNF Therapy Has Failed2014/09/08
    A study in the September issue of Gastroenterology evaluated the effects of vedolizumab induction therapy for patients with Crohn's disease for whom tumor necrosis factor (TNF) antagonists have already failed. Dr. Kuemmerle speaks with Dr. Bruce E. Sands
  8. Factors That Could Affect Colorectal Cancer Screening Strategies2014/08/04
    Two related studies in the August issue of Gastroeneterology discuss factors that could affect colorectal cancer screening strategies, including age, sex, race, ethnicity, and whether or not repeat colonoscopy is advisable within ten years.
  9. Adverse Outcomes Associated with Drug-Induced Liver Injury2014/07/02
    A study in the July issue of Gastroenterology sheds new light on adverse outcomes associated with drug-induced liver injury. Dr. Kuemmerle speaks with author Dr. Robert J. Fontana
  10. Managing Celiac Disease Beyond a Gluten-Free Diet2014/05/30
    An editorial in the June issue of Gastroenterology discusses recent findings that could help physicians and patients manage celiac disease beyond a gluten-free diet. Dr. Kuemmerle speaks with author Dr. Sheila Crowe.
  11. Impact of the Hepatopulmonary Syndrome MELD Exception Policy on Outcomes of Patients After Liver Transplantation2014/05/01
    An article in the May issue of Gastroenterology analyzed the UNOS database to determine the impact of the HPS MELD exception policy on outcomes of post-liver transplantation patients. Dr. Kuemmerle speaks with author Dr. David S. Goldberg
  12. Anti-Tumor Necrosis Factor Monotherapy vs Combination Therapy for Inflammatory Bowel Disease2014/04/02
    An editorial in the April issue of Gastroenterology compares anti-tumor necrosis factor monotherapy with combination therapy for inflammatory bowel disease. Dr. Kuemmerle speaks with co-author Dr. Corey A. Siegel
  13. Telaprevir Twice Daily Is Noninferior to Telaprevir Every 8 Hours for Chronic Hepatitis C2014/03/21
    A study in the March issue of Gastroenterology examined the safety and efficacy of 2X daily telaprevir in treatment-naive patients with chronic HCV genotype 1 infection, including those with cirrhosis. Dr. Kuemmerle speaks to author Dr. Maria Buti.
  14. Efficacy of an Interferon-and-Ribavirin-Free Regimen of Direct-Acting Antivirals in Patients with Chronic HCV Infection2014/02/04
    A study in the February issue of Gastroenterology examined the safety and efficacy of an interferon-free, ribavirin-free regimen of direct-acting antivirals in patients with chronic HCV infection. Dr. Kuemmerle speaks to Dr. Gregory T. Everson.
  15. Subcutaneous Golimumab Induces and Maintains Clinical Response and Remission in Patients with Moderate-to-Severe Ulcerative Colitis2014/01/31
    Two studies in the January issue of Gastroenterology show that subcutaneous golimumab induces and maintains clinical response and remission in patients with moderate-to-severe ulcerative colitis; Dr. Kuemmerle speaks to Dr. Brian G. Feagan
  16. Association Between Alanine Aminotransferase and Risk Factors for Atherogenesis2013/12/03
    A study in the December issue of Gastroenterology examined the relationship between low–normal and high–normal levels of alanine aminotransferase (ALT) and various cardiovascular risk factors; Dr. Kuemmerle speaks to first author Dr. M. Shadab Siddiqui
  17. Long-term Intake of Dietary Fiber and Risk of Crohn's Disease and Ulcerative Colitis2013/11/05
    A prospective study in the November issue of Gastroenterology looked at associations between long-term intake of dietary fiber and risk of incident Crohn's disease or ulcerative colitis; Dr. Kuemmerle speaks to Dr. Ashwin Ananthakrishnan.
  18. Early Administration of Azathioprine in Treatment of Crohn's Disease2013/10/03
    Two related studies in the October issue of Gastroenterology look at early administration of azathioprine in the management of patients with Crohn's disease.
  19. Pathogenesis of Primary Sclerosing Cholangitis and Advances in Diagnosis and Management2013/09/07
    A review article in the September issue of Gastroenterology takes a comprehensive look at current understanding of primary sclerosing cholangitis (PSC) and discusses important topics for future studies
  20. No Effects of Gluten in Patients with Self-Reported Non-Celiac Gluten Sensitivity After Dietary Reduction of FODMAPs2013/08/01
    A study in the August Gastroenterology found no effect of gluten in patients with non-celiac gluten sensitivity after also reducing fermentable, poorly absorbed, short-chain carbohydrates. Dr. Kuemmerle speaks to Dr. Peter GIbson
  21. Should Surveillance After Radiofrequency Ablation of Barrett's Esophagus Be Stopped? A Glass Half Full2013/07/03
    Three studies in the July issue of Gastroenterology report on the durability of radiofrequency ablation therapy for Barrett's esophagus. Dr. Kuemmerle speaks to the author of an editorial accompanying the studies, Dr. Douglas A. Corley.
  22. Defining Acute-on-Chronic Liver Failure in the East and West2013/06/04
    An editorial in the June issue of Gastroenterology discusses the urgent need to establish a worldwide definition for acute-on-chronic liver failure (ACLF). Dr. Kuemmerle speaks to author Dr. Jasmohan S Bajaj.
  23. A Historical Perspective on Clinical Advances in Pancreatic Diseases2013/05/03
    This year's annual, special “13th” issue of Gastorenterology is entitled, “The Pancreas: Biology, Diseases, and Therapy.” Dr. Kuemmerle speaks to Dr. Anil Rustgi, author of a commentary in that issue on history of clinical advances in pancreatic disease.
  24. Hepatocellular Benign Tumors: Classification and Care2013/05/03
    A review article in the May issue of Gastroenterology looks at the molecular pathways involved in benign hepatocellular tumors and discusses how this basic knowledge has been progressively translated into personalized clinical care.
  25. Uncovering Hidden Information in Achalasia Using Esophageal Pressure Topography2013/04/04
    An editorial in the April issue of Gastroenterology looks at how the introduction of esophageal pressure topography has changed our understanding of achalasia and esophageal motor diseases. Dr. Kuemmerle speaks to author Dr. John E. Pandolfino of Northwes
  26. CDC and USPSTF 2012 Screening Recommendations for Hepatitis C Virus Infection2013/03/01
    . A commentary in the March of Gastroenterology takes an overview of recent differing screening recommendations from the CDC and USPSTF for Hepatitis C Virus Infection. Dr. Kuemmerle speaks to Dr. Fasiha Kanwal
  27. Phenotypic Identification and Classification of Functional Defecatory Disorders Using High-Resolution Anorectal Manometry2013/02/01
    A study in the February issue of Gastroenterology sought to characterize phenotypic variation in constipated patients through high-resolution anorectal manometry. Dr. Kuemmerle discusses the results with Dr. Adil Bharucha of the Mayo Clinic.
  28. When the Spleen Gets Tough, the Varices Get Going2013/01/04
    Two papers in the January issue of Gastroenterology seek to identify noninvasive tests that can evaluate patients w/ cirrhosis for complications such as portal hypertension and varices. Dr. Kuemmerle speaks to editorial co-author Dr. Guadalupe Garcia-Tsao
  29. Efficacies of Biliary and Pancreatic Sphincterotomy in Treatment of Idiopathic Recurrent Acute Pancreatitis2012/12/04
    A study in the December issue of Gastroenterology finds that among patients with pancreatic sphincter dysfunction, biliary sphincterotomy or a combination of biliary and pancreatic sphincterotomy similarly prevent acute pancreatitis; with Dr. Gregory Cote
  30. Hormone Therapy Increases Risk of Ulcerative Colitis, But Not Crohn's Disease2012/11/02
    A study in the November issue of Gastroenterology found that postmenopausal hormone therapy was associated with an increased risk of ulcerative colitis, but not Crohn's disease. Dr. Kuemmerle discusses these findings with Dr. Andrew T. Chan.
  31. New Risk-Stratification Biomarker Panel for Barrett's Esophagus2012/09/28
    A new population-based study in the October issue of Gastroenterology reveals a new risk-stratification biomarker panel for Barrett's esophagus. Dr. Kuemmerle speaks with author Dr. Rebecca C. Fitzgerald.
  32. Guidelines for Colonoscopy Surveillance After Screening and Polypectomy2012/08/30
    The US Multi-Society Task Force on Colorectal Cancer has revised and updated its guidelines for colonoscopy surveillance after screening and polypectomy. Dr. Kuemmerle speaks to author Dr. David A. Lieberman of Oregon Health and Science University
  33. Management of Barrett's Dysplasia and Early-Stage Esophageal Adenocarcinoma2012/08/01
    An article in the August issue of Gastroenterology provides consensus recommendations for management of Barrett's dysplasia and early-stage esophageal adenocarcinoma. Dr. Kuemmerle speaks w/ author Dr. Jausz Jankowski.
  34. Multi-Society Sedation Curriculum for Gastrointestinal Endoscopy2012/06/27
    The MSCGE was developed by the four national GI societies to address the need for a complete and programmatic approach to the training of procedure sedation. Dr. Kuemmerle speaks to Committee Chair Dr. John Vargo about the curriculum.
  35. Multi-Society Guideline for the Diagnosis and Management of Non-alcoholic Fatty Liver Disease2012/06/01
    Three GI societies have developed a new practice guideline for the diagnosis and management of Non-Alcoholic Fatty Liver Disease. Dr. Kuemmerle speaks to author Dr. Naga Chalasani about these recommendations.
  36. Hepatic Cell–Type Specific Gene Expression is a Better Predictor of HCV Treatment Outcome than IL28B Genotype2012/04/24
    A study in the May issue of Gastroenterology finds that cell-type–specific expression pattern of ISGs varies among patients with different IL28B genotypes and is a strong predictor of response to interferon-based treatment. Featuring Dr. Jordan Feld.
  37. Role of Obesity and Lipotoxicity in the Development of Nonalcoholic Steatohepatitis2012/03/27
    A comprehensive review article in the April issue of Gastroenterology looks at the role of obesity and lipotoxicity in the development of nonalcoholic steatohepatitis. Dr. Kuemmerle speaks to author Dr. Kenneth Cusi.
  38. GC-SF Mobilizes CD34+ Cells and Improves Survival of Patients with Acute-on-Chronic Liver Failure2012/03/02
    A study in the March issue of Gastroenterology examined whether mobilization of bone marrow–derived stem cells with granulocyte colony–stimulating factor (G-CSF) might promote hepatic regeneration for patients with acute-on-chronic liver failure (ACLF).
  39. Next-Generation Stool DNA Test Accurately Detects Colorectal Cancer and Large Adenomas2012/02/21
    A study in the February issue of Gastroenterology assessed colorectal neoplasm detection by a next-generation sDNA test and effects of covariates on test performance. Dr. Kuemmerle speaks to first author Dr. David A. Ahlquist
  40. Maintenance of Remission Among Patients With Crohn's Disease on Antimetabolite Therapy Following Infliximab Therapy2011/12/22
    Maintenance of Remission Among Patients With Crohn's Disease on Antimetabolite Therapy After Infliximab Therapy Is Stopped. Dr. Kuemmerle speaks to the first author of this study in the January issue of Gastroenterology, Prof. Edouard Louis.
  41. Current Interferon-Free Treatment Regimens for Hepatitis C2011/12/01
    An editorial in the December issue of Gastroenterology looks at the development of DAAs directed at multiple targets in the HCV life cycle and asks, “Are we ready for interferon-free treatment regimens?” Dr. Kuemmerle speaks to co-author Dr. Anna Lok
  42. Increased Risk of Nonmelanoma Skin Cancers Among Individuals With IBD2011/11/01
    A study in the November issue of Gastroenterology looks at the risk of nonmelanoma skin cancer (NMSC) among individuals with inflammatory bowel disease (IBD). Dr. Kuemmerle speaks to study co-author Dr. Harminder Singh
  43. Prevalence of Celiac Disease Among Patients With Nonconstipated Irritable Bowel Syndrome2011/10/01
    A study in the October issue of Gastroenterology evaluated the prevalence of celiac disease antibodies and biopsy-confirmed CD among patients with nonconstipated IBS in a large US population. Dr. Kuemmerle speaks to author Dr. Brooks Cash.
  44. Changes in Postprandial Lipid Clearance and Blood Glucose Homeostasis Following Vertical Sleeve Gastrectomy in Rats2011/09/01
    Two studies in the September issue of Gastroenterology look at the effects of vertical sleeve gastrectomy (VSG) on plasma lipid levels and metabolism. Dr. Kuemmerle speaks to two of the co-authors of both studies.
  45. Durability of Radiofrequency Ablation in Barrett's Esophagus with Dysplasia2011/08/02
    A study in the August issue of Gastroenterology assessed long-term rates of eradication, safety, and durability of radiofrequency ablation in patients with Barrett's esophagus. Dr. Kuemmerle speaks to author Dr. Nicholas Shaheen of UNC Chapel Hill
  46. Fruit, Vegetables, and Folate: The Evidence for Cancer Prevention2011/07/01
    Two studies in the July issue of Gastroenterology examine the relationship between fruits, vegetables, folate, and colorectal cancer, and suggest that potential associations are more complex than first considered. Dr. Kuemmerle speaks to Dr. Andrew Chan
  47. Functions of Autophagy in Hepatic and Pancreatic Physiology and Disease2011/06/03
    A review in the June issue of Gastroenterology discusses the effects of autophagy on hepatic and pancreatic physiology, and the contribution of this degradative process to diseases of the liver and pancreas. Dr. Kuemmerle speaks with author Dr. Mark Czaja
  48. Aspirin or Nonsteroidal Anti-inflammatory Drug Use Increases Risk for Diverticulitis and Diverticular Bleeding2011/05/06
    A study in the May issue of Gastroenterology examines the influence of aspirin and NSAID use on risk of diverticulitis and diverticular bleeding in a large prospective cohort. Dr. Kuemmerle speaks w/ author Dr. Lisa Strate of the University of Washington
  49. Microscopic Colitis2011/04/05
    A comprehensive review on recent findings about the clinical features, diagnosis, epidemiology, pathophysiology, and treatment of microscopic colitis appears in the April issue of Gastroenterology. Dr. Kuemmerle speaks with co-author Dr. Darrell S. Pardi.
  50. Management of Barrett's Esophagus2011/03/18
    The AGA releases its medical position statement and technical review on the management of Barrett's esophagus in the March issue of Gastroenterology. Dr. Kuemmerle speaks with a co-author of both documents, Dr. John Inadomi.
  51. Changes in Insulin Sensitivity and Body Weight Due to Peginterferon and Ribavirin Therapy for Hepatitis C2011/02/18
    A study in the February Gastroenterology looks at changes in insulin resistance and weight in patients with chronic hepatitis C during and after peginterferon and ribavirin therapy. Dr. Kuemmerle speaks with lead author Dr. Hari S. Conjeevaram.
  52. Prevalence of NAFLD and NASH Utilizing Ultrasound and Liver Biopsy2011/01/20
    An important study in the January Gastroenterology looks at the prevalence of NAFLD and NASH among a group of patients utilizing ultrasound and liver biopsy. Dr. Kuemmerle speaks with author Dr. Stephen A. Harrison.
  53. Gastrointestinal Microbial Profiles Vary With IBD Phenotypes2010/12/01
    A Pyrosequencing study of twins in the December Gastroenterology looked at the role of gastrointestinal microbiota in the etiology of IBD. Dr. Kuemmerle interviews author Dr. Lars Engstrand
  54. Serrated Polyps and Neoplasia2010/10/29
    A study in the November issue of Gastroenterology investigates whether detection of proximal nondysplastic serrated polyps (ND-SP) at screening and surveillance colonoscopies is associated with advanced neoplasia.
  55. Safety of Proton Pump Inhibitor Exposure2010/10/05
    Dr. Kuemmerle speaks to co-author Dr. David Metz about a review article in the October 2010 Gastroenterology on safety of proton pump inhibitor exposure.
  56. Acoustic Cough: Reflux Associations in Chronic Cough2010/09/01
    The authors of a study in the September issue of Gastroenterology explored the temporal association between cough and gastroesophageal reflux (GOR) in patients in whom non-GOR causes have been excluded.
  57. Achalasia: The Disease and Current Treatment2010/07/30
    Achalasia is the subject of a mini-review in the August issue of Gastroenterology. Dr. Kuemmerle speaks to author Dr. David Katzka. Also, a new feature on the latest stories from GI and Hepatology News.
  58. Detecting Celiac Disease and Lymphocytic Enteropathy by Parallel Serology and Histopathology2010/06/29
    A prospective study to determine the clinical, pathologic, and serologic spectrum of celiac disease in a general population appears in the July issue of Gastroenterology.
  59. Factors in the Development and Progression of Gastroesophageal Varices in Chronic Hepatitis C Patients2010/06/01
    A study in the June 2010 issue of Gastroenterology looks at gastroesophageal variceal formation and progression in a large cohort of patients with chronic hepatitis C and advanced fibrosis. Dr. Kuemmerle speaks with author Dr. Robert J. Fontana.
  60. Colorectal Cancer Screening Guidelines: The Importance of Evidence and Transparency2010/04/29
    Dr. Kuemmerle speaks with Dr. James E. Allison about his article in the May issue of Gastroenterology on colorectal cancer screening guidelines and deciding which test to recommend.
  61. Diagnosis and Treatment of Pelvic Floor Disorders2010/04/01
    A critical review of new diagnostic and treatment innovations for pelvic floor disorders appears in the April issue of Gastroenterology. Dr. Kuemmerle speaks with author Dr. Adil E. Bharucha.
  62. pCLE vs. Virtual Chromoendoscopy for Colon Polyp Classification2010/03/03
    A study in the March issue of Gastroenterology compares probe-based confocal laser endomicroscopy (pCLE) virtual chromoendoscopy for classification of colon polyps. Dr. Kuemmerle speaks to author Dr. Michael Wallace
  63. Colorectal Neoplasia in Inflammatory Bowel Disease2010/02/01
    An AGA medical position statement and technical review on the diagnosis and management of colorectal neoplasia in inflammatory bowel disease appear in the February 2010 issue of Gastroenterology. Dr. Kuemmerle speaks with author Dr. Francis A. Farraye.
  64. Radioembolization for Hepatocellular Carcinoma Using Yttrium-90 Microspheres2009/12/30
    A study in the January 2010 Gastroenterology assesses long-term clinical outcomes of Hepatocellular carcinoma patients treated with intra-arterial yttrium-90 microspheres. Dr. Kuemmerle speaks to senior author Dr. Riad Salem.
  65. Predicted Response of Chronic HBV Patients to Therapy with Peginterferon-Alfa2009/11/30
    A study in the December 2009 Gastroenterology looks at factors that predict response of patients with chronic hepatitis B virus (HBV) infection to therapy with pegylated interferon (PEG-IFN)–alfa.
  66. Gastroesophageal Reflux Might Cause Esophagitis Through a Cytokine-Mediated Mechanism Rather Than Caustic Acid Injury2009/10/26
    A study in the November 2009 Gastroenterology looks at a possible alternative concept for the development of reflux esophagitis.
  67. Colectomy Rate Comparison After Treatment of Ulcerative Colitis With Placebo or Infliximab2009/09/29
    A study in the October 2009 Gastroenterology compares colectomy rates following treatment of ulcerative colitis with placebo or infliximab
  68. Coinfection With HIV-1 and HCV — A One-Two Punch2009/08/31
    Dr. Arthur Kim of Massachusetts General Hospital discusses HIV-1 and HCV coinfection.
  69. Computed Tomographic Colonography: Current Perspectives and Future Directions2009/08/31
    Dr. Don Rockey discusses current perspectives and future directions of computed tomographic (CT) colonography
  70. Reducing Extracellular pH Sensitizes the Acinar Cell to Secretagogue-Induced Pancreatitis Responses in Rats2009/08/31
    A new study by Dr. Fred Gorelick examines whether or not exposure to an acid load might sensitize the acinar cell to secretagogue-induced pancreatitis.
  71. Fecal Incontinence in US Adults: Epidemiology and Risk Factors2009/07/31
    A study in the August 2009 issue of Gastroenterology set out to estimate the prevalence of different types and frequencies of fecal incontinence, describe demographic f
  72. A Cost-Utility Analysis of Ablative Therapy for Barrett's Esophagus2009/05/27
    Dr. Kuemmerle speaks with Dr. John Inadomi, author of a study in the June issue of Gastroenterology that compares the cost utility of ablation with that of endoscopic surveillance strategies.
  73. Heritability of Nonalcoholic Fatty Liver Disease2009/04/27
    Dr. Kuemmerle interviews Dr. Jeffrey Schwimmer, lead author of an article in the May Gastroenterology that studies the role of familial factors in identifying individuals at high risk for NAFLD. The second of two Gastroenterology podcasts for May 2009.
  74. Tests of Gastric Neuromuscular Function2009/04/27
    Dr. Kuemmerle speaks with Dr. Henry Parkman and Dr. Michael Jones, authors of a fascinating review article in the May Gastroenterology that describes tests of gastric function , provides the methodologies behind them and details the physiology that they a
  75. Prospective Derivation and Validation of a Clinical Prediction Rule for Recurrent Clostridium difficile Infection2009/03/30
    The authors of a study in the April issue of Gastroenterology have developed a clinical prediction rule for recurrent Clostridium difficile infection (CDI) that identifies high-risk patients likely to benefit from preventive measures against recurrence.
  76. A Combination of Therapies Improves Virologic Responses In Patients With Chronic Hepatitis C (Genotype 4)2009/03/04
    Dr. Kuemmerle, Dr. Emmet Keeffe and Dr. Michael W. Fried discuss study results that show the combination of nitazoxanide, peginterferon alfa-2a, and ribavirin improved percentages of patients with rapid virologic response (RVR) and sustained ...
  77. Infliximab Prevents Crohn's Disease Recurrence After Ileal Resection2009/02/27
    February 2009
  78. Presentation and Long Term Follow-Up of Refractory Celiac Disease - Comparison of Type I With Type II2008/12/29
    January 2009
Gastroenterology
http://gastrodev.org/podcasts/AGA/GASTRO/
An engaging, informative mix of author interviews and expert commentary on the latest articles from Gastroenterology, hosted by the AGA journals' online editor, John F. Kuemmerle, MD, AGAF.


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